Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00876 |
Legumain Protein, Mouse, Recombinant (His)
AI746452,AEP,AU022324,Prsc1,legumain |
Mouse | HEK293 Cells |
Legumain Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.8 kDa and the accession number is A2RTI3. | |||
TMPK-01146 |
LGMN Protein, Human, Recombinant (His)
AI746452,Legumain,LGMN1,Prsc1,AEP,LGMN,AU022324... |
Human | HEK293 Cells |
Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in the pathogenesis of Alzheimer's disease (AD). In single-variant association analysis, none of the common variants in LGMN were statistically significant. In gene-based analysis, the LGMN gene also showed no association with AD. |